Xanax XR 0.5mg

(6 customer reviews)

$395.00$685.00

Generic Name : Alprazolam

Imprint : X 0.5

Strength : 0.5 mg

Color : White

Size : 9.00 mm

Shape : Five-sided

Availability : No prescription needed

Class : Benzodiazepines

Pregnancy Category : D – Positive evidence of risk

CSA Schedule : 4 – Some potential for abuse

Labeler / Supplier : Pfizer U.S. Pharmaceuticals Group

National Drug Code (NDC) : 00009-0057

 

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Description

Xanax XR Description

Xanax XR 0.5mg For Sale contains alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds. The chemical name of alprazolam is 8-chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-α] [1,4] benzodiazepine. The molecular formula is C17H13ClN4 which corresponds to a molecular weight of 308.76.

The structural formula is:

Alprazolam is a white crystalline powder, which is soluble in methanol or ethanol but which has no appreciable solubility in water at physiological pH.

Each Xanax XR extended-release tablet, for oral administration, contains 0.5 mg, 1 mg, 2 mg, or 3 mg of alprazolam. The inactive ingredients are colloidal silicon dioxide, hypromellose, lactose, and magnesium stearate. In addition, the 1 mg and 3 mg tablets contain D & C yellow No. 10 and the 2 mg and 3 mg tablets contain FD&C blue No. 2.

 

Xanax XR 0.5mg For Sale Medication Guide

Xanax XR (ZAN-aks XR)

(alprazolam) extended-release tablets, C-IV

What is the most important information I should know about Xanax XR?

Xanax XR is a benzodiazepine medicine. Taking benzodiazepines with opioid medicines, alcohol, or other central nervous system (CNS) depressants (including street drugs) can cause severe drowsiness, breathing problems (respiratory depression), coma and death. Get emergency help right away if any of the following happens:

o shallow or slowed breathing

o breathing stops (which may lead to the heart stopping)

o excessive sleepiness (sedation)

Do not drive or operate heavy machinery until you know how taking Xanax XR with opioids affects you.

Risk of abuse, misuse, and addiction. There is a risk of abuse, misuse, and addiction with benzodiazepines including Xanax XR which can lead to overdose and serious side effects including coma and death.

o Serious side effects including coma and death have happened in people who have abused or misused benzodiazepines, including Xanax XR. These serious side effects may also include delirium, paranoia, suicidal thoughts or actions, seizures, and difficulty breathing. Call your healthcare provider or go to the nearest hospital emergency room right away if you get any of these serious side effects.

o You can develop an addiction even if you take Xanax XR as prescribed by your healthcare provider.

o Take Xanax XR exactly as your healthcare provider prescribed.

o Do not share your Xanax XR with other people.

o Keep Xanax XR in a safe place and away from children.

Physical dependence and withdrawal reactions. Xanax XR can cause physical dependence and withdrawal reactions.

o Do not suddenly stop taking Xanax XR. Stopping Xanax XR suddenly can cause serious and life-threatening side effects, including, unusual movements, responses, or expressions, seizures, sudden and severe mental or nervous system changes, depression, seeing or hearing things that others do not see or hear, an extreme increase in activity or talking, losing touch with reality, and suicidal thoughts or actions. Call your healthcare provider or go to the nearest hospital emergency room right away if you get any of the following symptoms.

o Some people who suddenly stop benzodiazepines, have symptoms that can last for several weeks to more than 12 months, including, anxiety, trouble remembering, learning, or concentrating, depression, problems sleeping, feeling like insects are crawling under your skin, weakness, shaking, muscle twitching, burning or prickling feeling in your hands, arms, legs or feet, and ringing in your ears.

o Physical dependence is not the same as drug addiction. Your healthcare provider can tell you more about the differences between physical dependence and drug addiction.

o Do not take more Xanax XR than prescribed or take Xanax XR for longer than prescribed.

What is Xanax XR?

Xanax XR is a prescription medicine used to treat panic disorder, with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia)

Xanax XR is a federal controlled substance (C-IV) because it contains alprazolam that can be abused or lead to dependence. Keep Xanax XR in a safe place to prevent misuse and abuse. Selling or giving away Xanax XR may harm others and is against the law. Tell your healthcare provider if you have abused or been dependent on alcohol, prescription medicines or street drugs.

It is not known if Xanax XR is safe and effective in children.

Elderly patients are especially susceptible to dose related adverse effects when taking Xanax XR.

It is not known if Xanax XR is safe and effective in the treatment of panic disorder for use longer than 8 weeks.

Do not take Xanax XR if:

you are allergic to alprazolam, other benzodiazepines, or any of the ingredients in Xanax XR. See the end of this Medication Guide for a complete list of ingredients in Xanax XR.

you are taking antifungal medicines including ketoconazole and itraconazole

Before you take Xanax XR, tell your healthcare provider about all of your medical conditions, including if you:

have or have had depression, mood problems, or suicidal thoughts or behavior

have liver or kidney problems

have lung disease or breathing problems

are pregnant or plan to become pregnant.

o Taking Xanax XR late in pregnancy may cause your baby to have symptoms of sedation (breathing problems, sluggishness, low muscle tone), and/or withdrawal symptoms (jitteriness, irritability, restlessness, shaking, excessive crying, feeding problems).

o Tell your healthcare provider right away if you become pregnant or think you are pregnant during treatment with Xanax XR.

o There is a pregnancy registry for women who take Xanax XR during pregnancy. The purpose of the registry is to collect information about the health of you and your baby. If you become pregnant during treatment with Xanax XR, talk to your healthcare provider about registering with the National Pregnancy Registry for Psychiatric Medications. You can register by calling 1-866-961-2388 or visiting https://womensmentalhealth.org/research/pregnancyregistry/.

are breastfeeding or plan to breastfeed. Xanax XR passes into your breast milk.

o Talk to your healthcare provider about the best way to feed your baby if you take Xanax XR.

o Breastfeeding is not recommended during treatment with Xanax XR.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Taking Xanax XR with certain other medicines can cause side effects or affect how well Xanax XR or the other medicines work. Do not start or stop other medicines without talking to your healthcare provider.

How should I take Xanax XR?

See “What is the most important information I should know about Xanax XR?”

Take Xanax XR exactly as your healthcare provider tells you to take it. Your healthcare provider will tell you how much Xanax XR to take and when to take it.

If you take too much Xanax XR, call your healthcare provider or go to the nearest hospital emergency room right away.

Swallow Xanax XR tablets whole. Do not crush, chew or break Xanax XR.

What are the possible side effects of Xanax XR?

Xanax XR may cause serious side effects, including:

See “What is the most important information I should know about Xanax XR?”

Seizures. Stopping Xanax XR can cause seizures and seizures that will not stop (status epilepticus).

Mania. Xanax XR may cause an increase in activity and talking (hypomania and mania) in people who have depression.

Xanax XR can make you sleepy or dizzy and can slow your thinking and motor skills.

o Do not drive, operate heavy machinery, or do other dangerous activities until you know how Xanax XR affects you.

o Do not drink alcohol or take other drugs that may make you sleepy or dizzy while taking Xanax XR without first talking to your healthcare provider. When taken with alcohol or drugs that cause sleepiness or dizziness, Xanax XR may make your sleepiness or dizziness much worse.

The most common side effects of Xanax XR include:

sleepiness

trouble saying words clearly (dysarthria)

problems with memory

problems with coordination

changes in sex drive (libido)

constipation

nausea

These are not all the possible side effects of Xanax XR. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store Xanax XR?

Store Xanax XR at room temperature between 68°F to 77°F (20°C to 25°C)

Keep Xanax XR and all medicines out of the reach of children.

General information about the safe and effective use of Xanax XR.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide.

Do not use Xanax XR for a condition for which it was not prescribed.

Do not give Xanax XR to other people, even if they have the same symptoms that you have. It may harm them.

You can ask your pharmacist or healthcare provider for information about Xanax XR that is written for health professionals.

What are the ingredients in Xanax XR?

Active ingredient: alprazolam

Inactive ingredients: lactose, magnesium stearate, colloidal silicon dioxide, and hypromellose. In addition, the 1 mg and 3 mg tablets contain D & C yellow No. 10 and the 2 mg and 3 mg tablets contain FD&C blue No. 2.

XANAX® XR is a registered trademark of UPJOHN US 2 LLC, a Viatris Company.

For more information, call Viatris at 1-877-446-3679 (1-877-4-INFO-RX).

Distributed by:
Viatris Specialty LLC
Morgantown, WV 26505 U.S.A.

UPJ:MG:XNXXRT:RX2

 

Xanax XR Supply/Storage and Handling

Xanax XR 0.5mg For Sale is supplied in the following strengths and package configurations:

Xanax XR Tablets

Package Configuration

Tablet Strength (mg)

NDC

Print

Bottles of 60

0.5 mg

NDC 0009-0057-07

white, pentagonal shaped tablets debossed with an “X” on one side and “0.5” on the other side

Bottles of 60

1 mg

NDC 0009-0059-07

yellow, square shaped tablets debossed with an “X” on one side and “1” on the other side

Bottles of 60

2 mg

NDC 0009-0066-07

blue, round shaped tablets debossed with an “X” on one side and “2” on the other side

Bottles of 60

3 mg

NDC 0009-0068-07

green, triangular shaped tablets debossed with an “X” on one side and “3” on the other side

 

Risks from Concomitant Xanax Use with Opioids

Concomitant use of Xanax, and opioids may result in profound sedation, respiratory depression, coma, and death. Because of these risks, reserve concomitant prescribing of these drugs in patients for whom alternative treatment options are inadequate.

Observational studies have demonstrated that concomitant use of opioid analgesics and benzodiazepines increases the risk of drug-related mortality compared to use of opioids alone. If a decision is made to prescribe Xanax XR 0.5mg For Sale concomitantly with opioids, prescribe the lowest effective dosages and minimum durations of concomitant use, and follow patients closely for signs and symptoms of respiratory depression and sedation. In patients already receiving an opioid analgesic, prescribe a lower initial dose of Xanax than indicated in the absence of an opioid and titrate based on clinical response. If an opioid is initiated in a patient already taking Xanax, prescribe a lower initial dose of the opioid and titrate based upon clinical response.

We would like to thank you for choosing us for your Xanax XR 0.5mg For Sale supplies, We really appreciate your orders. We hope that we can make you our long term customer, As you will be for sure completely satisfied with your order, so, in-turn, we expect your orders to grow and thrive in the near future as we value the relationships we develop with our customers. We make every effort to ship every order on time. 

Xanax XR 0.5mg For Sale Postmarketing Experience

The following adverse reactions have been identified during postapproval use of Xanax. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

  • Endocrine disorders: Hyperprolactinemia
  • General disorders and administration site conditions: Edema peripheral
  • Hepatobiliary disorders: Hepatitis, hepatic failure
  • Investigations: Liver enzyme elevations
  • Psychiatric disorders: Hypomania, mania
  • Reproductive system and breast disorders: Gynecomastia, galactorrhea
  • Skin and subcutaneous tissue disorders: Photosensitivity reaction, angioedema, Stevens-Johnson syndrome

 

Xanax Overdosage

Overdosage of benzodiazepines is characterized by central nervous system depression ranging from drowsiness to coma. In mild to moderate cases, symptoms can include drowsiness, confusion, dysarthria, lethargy, hypnotic state, diminished reflexes, ataxia, and hypotonia. Rarely, paradoxical or disinhibitory reactions (including agitation, irritability, impulsivity, violent behavior, confusion, restlessness, excitement, and talkativeness) may occur. In severe overdosage cases, patients may develop respiratory depression and coma. Overdosage of benzodiazepines in combination with other CNS depressants (including alcohol and opioids) may be fatal. Markedly abnormal (lowered or elevated) blood pressure, heart rate, or respiratory rate raise the concern that additional drugs and/or alcohol are involved in the overdosage.

In managing benzodiazepine overdosage, employ general supportive measures, including intravenous fluids and airway management. Flumazenil, a specific benzodiazepine receptor antagonist indicated for the complete or partial reversal of the sedative effects of benzodiazepines in the management of benzodiazepine overdosage, can lead to withdrawal and adverse reactions, including seizures, particularly in the context of mixed overdosage with drugs that increase seizure risk (e.g., tricyclic and tetracyclic antidepressants) and in patients with long-term benzodiazepine use and physical dependency. The risk of withdrawal seizures with flumazenil use may be increased in patients with epilepsy. Flumazenil is contraindicated in patients who have received a benzodiazepine for control of a potentially life-threatening condition (e.g., status epilepticus). If the decision is made to use flumazenil, it should be used as an adjunct to, not as a substitute for, supportive management of benzodiazepine overdosage. See the flumazenil injection Prescribing Information before use.

Xanax XR 0.5mg For Sale Drug Interactions

Drugs Having Clinically Important Interactions with Xanax XR 0.5mg For Sale

Table  includes clinically significant drug interactions with Xanax XR 0.5mg For Sale.

Opioids

Clinical implication

The concomitant use of benzodiazepines and opioids increases the risk of respiratory depression because of actions at different receptor sites in the CNS that control respiration. Benzodiazepines interact at gamma-aminobutyric acid (GABAA) sites and opioids interact primarily at mu receptors. When benzodiazepines and opioids are combined, the potential for benzodiazepines to significantly worsen opioid‑related respiratory depression exists.

Prevention or management

Limit dosage and duration of concomitant use of Xanax XR and opioids, and monitor patients closely for respiratory depression and sedation.

Examples

Morphine, buprenorphine, hydromorphone, oxymorphone, oxycodone, fentanyl, methadone, alfentanil, butorphanol, codeine, dihydrocodeine, meperidine, pentazocine, remifentanil, sufentanil, tapentadol, tramadol.

CNS Depressants

Clinical implication

The benzodiazepines, including alprazolam, produce additive CNS depressant effects when coadministered with other CNS depressants.

Prevention or management

Limit dosage and duration of Xanax XR during concomitant use with CNS depressants.

Examples

Psychotropic medications, anticonvulsants, antihistaminics, ethanol, and other drugs which themselves produce CNS depression.

Strong Inhibitors of CYP3A (except ritonavir)

Clinical implication

Concomitant use of Xanax XR with strong CYP3A inhibitors has a profound effect on the clearance of alprazolam, resulting in increased concentrations of alprazolam and increased risk of adverse reactions.

Prevention or management

Concomitant use of Xanax XR with a strong CYP3A4 inhibitor (except ritonavir) is contraindicated.

Examples

Ketoconazole, itraconazole, clarithromycin

Moderate or Weak Inhibitors of CYP3A

Clinical implication

Concomitant use of Xanax XR with CYP3A inhibitors may increase the concentrations of Xanax XR, resulting in increased risk of adverse reactions.

Prevention or management

Avoid use and consider appropriate dose reduction when Xanax XR is coadministered with a moderate or weak CYP3A inhibitor.

Examples

Nefazodone, fluvoxamine, cimetidine, erythromycin

CYP3A Inducers

Clinical implication

Concomitant use of CYP3A inducers can increase alprazolam metabolism and therefore can decease plasma levels of alprazolam.

Prevention or management

Caution is recommended during coadministration with alprazolam.

Examples

Carbamazepine, phenytoin

Ritonavir

Clinical implication

Interactions involving ritonavir and alprazolam are complex and time dependent. Short term administration of ritonavir increased alprazolam exposure due to CYP3A4 inhibition. Following long term treatment of ritonavir (> 10 – 14 days), CYP3A4 induction offsets this inhibition.

Alprazolam exposure was not meaningfully affected in the presence of ritonavir.

Prevention or management

Reduce Xanax XR dose when a patient is initiated with ritonavir and Xanax XR concomitantly, or when ritonavir is added to a regimen where Xanax XR is stabilized.

Increase Xanax XR dosage to the target dosage after 10 to 14 days of dosing ritonavir and Xanax XR concomitantly. No dosage adjustment of XANXR XR is necessary in patients receiving ritonavir for more than 10 to 14 days.

Concomitant use of Xanax XR with a strong CYP3A inhibitor, except ritonavir, is contraindicated.

Digoxin

Clinical implication

Increased digoxin concentrations have been reported when alprazolam was given, especially in geriatric patients (>65 years of age).

Prevention or management

In patients on digoxin therapy, measure serum digoxin concentrations before initiating Xanax XR. Continue monitoring digoxin serum concentration and toxicity frequently. Reduce the digoxin dose if necessary.

 

Refunds Policy

If something isn’t right, we are happy to process a return. We believe in secure eCommerce and will provide a 30-day money back guarantee for the products and services that are bought online. All refund applications will be carefully considered and given at the discretion of Company Management. Please read through our policy below then follow the instructions.

Faulty or Incorrectly Sent Items

A refund can be processed in the following circumstances; 

  • If an item is faulty, 
  • Has been damaged in transit, 
  • Does not perform in accordance with advertised claims or specification; and/or 
  • Has been sent to you incorrectly. 

We will pay for postage to return the goods in this instance and will either reship the correct item or arrange a refund.

Change of Mind

We will happily accept a return of a order for a refund or credit if you simply change your mind, on the following conditions:

  • The package is received in its original condition (has not been opened, used, damaged)
  • The package is NOT a pharmacy medicine/prescription, vitamin, baby formula, or adult product
  • The package has been ordered from our online pharmacy within the last 14 days
  • Postage is paid by the customer

Returns Process

In order to be eligible for the money back guarantee we must be notified within 30 days (or 14 for change of mind returns).

  1. Please submit your return request form: This can be accessed once logged into your Pharmacy Direct customer account. Please navigate to My Account then select Order History click the Eye Icon to select the appropriate order.  Then select the red/black arrow icon of the item for return. Complete the return request form. Once submitted our customer care team will be in touch within 24-48 hours with further details. Alternatively, you can contact our Customer Care Team directly by Email: sales@xanax4anxiety.com. 
  2. If you are posting the goods back to us, please use the box your original order arrived in. We are unable to process a refund if any returned goods are damaged in transit.
  3. Please use the correct return address, depending on the return type. We recommend using registered post as we do not take responsibility for lost, unregistered returns. (this will be advised by the Customer Care team member processing your return).

Please note: returns of ‘Special Orders’ will NOT be accepted. These include, but are not limited to: bulk quantities (considered greater than the average consumer quantities) and wholesaler purchases.

 

Delivery Policy

All orders are shipped 24/7 (Everyday). Please remember that all the packages are to be signed, so it’s advisable to ensure that you provide the correct details like your phone number and shipping address before you buy Xanax online from us.

Note: If your address is a P.O BOX, then you will be asked to collect the package from your local post office after you show proof of purchase.

What’s the delivery cost?

We charge $50 for express delivery, $75 for overnight delivery and $100 for international deliveries. There’s also an option for free delivery for US & Canada but this option only applies for orders higher $2000. 

How to my track my order?

As soon as your placed order is shipped, we will send you an email along with the tracking details. You can click the tracking link which you received in the mail to check and track your package status anytime-anywhere. It is advised to check your spam folder, sometimes our emails end up there also.

Do I need to be present when you deliver?

Anyone can sign and receive your package on your behalf. Using our tracking mail, you might get the notification mail once it reaches the local post office. From there, you can schedule the delivery of your Xanax and pickup according to your convenience.

What’s the estimated time of delivery?

The typical ETA is

  • 1 – 2 Days for US & Canada delivery
  • 3 Days for express delivery
  • 4-8 Days for international delivery

 

Do you offer overnight shipping of medications?

Yes, we offer overnight delivery via multiple courier agencies for all of our products.

Additional information

Xanax Quantity

120 Pills, 150 Pills, 180 Pills, 90 Pills

Product Description

Xanax For Sale Description

XANAX Tablets contain alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds. The chemical name of alprazolam is 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-α] [1,4] benzodiazepine. Alprazolam is a white crystalline powder, which is soluble in methanol or ethanol but which has no appreciable solubility in water at physiological pH. Each XANAX Tablet, for oral administration, contains 0.25, 0.5, 1 or 2 mg of alprazolam. Inactive ingredients: Cellulose, corn starch, docusate sodium, lactose, magnesium stearate, silicon dioxide and sodium benzoate. In addition, the 0.5 mg tablet contains FD&C Yellow No. 6 and the 1 mg tablet contains FD&C Blue No. 2.

CLINICAL PHARMACOLOGY

Pharmacodynamics

CNS agents of the 1,4 benzodiazepine class presumably exert their effects by binding at stereo specific receptors at several sites within the central nervous system. Their exact mechanism of action is unknown. Clinically, all benzodiazepines cause a dose-related central nervous system depressant activity varying from mild impairment of task performance to hypnosis.

Pharmacokinetics

Absorption; Following oral administration, alprazolam is readily absorbed. Peak concentrations in the plasma occur in 1 to 2 hours following administration. Plasma levels are proportionate to the dose given; over the dose range of 0.5 to 3.0 mg, peak levels of 8.0 to 37 ng/mL were observed. Using a specific assay methodology, the mean plasma elimination half-life of alprazolam has been found to be about 11.2 hours (range: 6.3-26.9 hours) in healthy adults.

Distribution; In vitro, alprazolam is bound (80 percent) to human serum protein. Serum albumin accounts for the majority of the binding.

Metabolism/Elimination; Alprazolam is extensively metabolized in humans, primarily by cytochrome P450 3A4 (CYP3A4), to two major metabolites in the plasma: 4-hydroxyalprazolam and αhydroxyalprazolam. A benzophenone derived from alprazolam is also found in humans. Their half-lives appear to be similar to that of alprazolam. The plasma concentrations of 4­ hydroxyalprazolam and α-hydroxyalprazolam relative to unchanged alprazolam concentration were always less than 4%. The reported relative potencies in benzodiazepine receptor binding experiments and in animal models of induced seizure inhibition are 0.20 and 0.66, respectively, for 4-hydroxyalprazolam and α-hydroxyalprazolam. Such low concentrations and the lesser potencies of 4-hydroxyalprazolam and α-hydroxyalprazolam suggest that they are unlikely to contribute much to the pharmacological effects of alprazolam. The benzophenone metabolite is essentially inactive. Alprazolam and its metabolites are excreted primarily in the urine.

Drug-Drug Interactions; Alprazolam is primarily eliminated by metabolism via cytochrome P450 3A (CYP3A). Most of the interactions that have been documented with alprazolam are with drugs that inhibit or induce CYP3A4. CYP3A inducers would be expected to decrease alprazolam concentrations and this has been observed in vivo. The oral clearance of alprazolam (given in a 0.8 mg single dose) was increased from 0.90±0.21 mL/min/kg to 2.13±0.54 mL/min/kg and the elimination t1/2 was shortened (from 17.1±4.9 to 7.7 ±1.7 h) following administration of 300 mg/day carbamazepine for 10 days (see PRECAUTIONS–Drug Interactions). However, the carbamazepine dose used in this study was fairly low compared to the recommended doses (1000-1200 mg/day); the effect at usual carbamazepine doses is unknown. The ability of alprazolam to induce human hepatic enzyme systems has not yet been determined. However, this is not a property of benzodiazepines in general. Further, alprazolam did not affect the prothrombin or plasma warfarin levels in male volunteers administered sodium warfarin orally.

Indications and Usage

Xanax For Sale Indications and Usage

Anxiety Disorders

XANAX Tablets (alprazolam) are indicated for the management of anxiety disorder (a condition corresponding most closely to the APA Diagnostic and Statistical Manual [DSMIII-R] diagnosis of generalized anxiety disorder) or the short-term relief of symptoms of anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic.

Generalized anxiety disorder is characterized by unrealistic or excessive anxiety and worry (apprehensive expectation) about two or more life circumstances, for a period of 6 months or longer, during which the person has been bothered more days than not by these concerns. At least 6 of the following 18 symptoms are often present in these patients: Motor Tension (trembling, twitching, or feeling shaky; muscle tension, aches, or soreness; restlessness; easy fatigability); Autonomic Hyperactivity (shortness of breath or smothering sensations; palpitations or accelerated heart rate; sweating, or cold clammy hands; dry mouth; dizziness or light-headedness; nausea, diarrhea, or other abdominal distress; flushes or chills; frequent urination; trouble swallowing or ‘lump in throat’); Vigilance and Scanning (feeling keyed up or on edge; exaggerated startle response; difficulty concentrating or ‘mind going blank’ because of anxiety; trouble falling or staying asleep; irritability). These symptoms must not be secondary to another psychiatric disorder or caused by some organic factor. Anxiety associated with depression is responsive to XANAX.

Panic Disorder

XANAX is also indicated for the treatment of panic disorder, with or without agoraphobia. Studies supporting this claim were conducted in patients whose diagnoses corresponded closely to the DSM-III-R/IV criteria for panic disorder.

Panic disorder (DSM-IV) is characterized by recurrent unexpected panic attacks, ie, a discrete period of intense fear or discomfort in which four (or more) of the following symptoms develop abruptly and reach a peak within 10 minutes: (1) palpitations, pounding heart, or accelerated heart rate; (2) sweating; (3) trembling or shaking; (4) sensations of shortness of breath or smothering; (5) feeling of choking; (6) chest pain or discomfort; (7) nausea or abdominal distress; (8) feeling dizzy, unsteady, lightheaded, or faint; (9) derealization (feelings of unreality) or depersonalization (being detached from oneself); (10) fear of losing control; (11) fear of dying; (12) paresthesias (numbness or tingling sensations); (13) chills or hot flushes. Demonstrations of the effectiveness of XANAX by systematic clinical study are limited to 4 months duration for anxiety disorder and 4 to 10 weeks duration for panic disorder; however, patients with panic disorder have been treated on an open basis for up to 8 months without apparent loss of benefit. The physician should periodically reassess the usefulness of the drug for the individual patient.

Contraindications and Warnings

XANAX FOR SALE CONTRAINDICATIONS

XANAX Tablets are contraindicated in patients with known sensitivity to this drug or other benzodiazepines. XANAX may be used in patients with open angle glaucoma who are receiving appropriate therapy, but is contraindicated in patients with acute narrow angle glaucoma.

XANAX is contraindicated with ketoconazole and itraconazole, since these medications significantly impair the oxidative metabolism mediated by cytochrome P450 3A (CYP3A) (see WARNINGS and PRECAUTIONS–Drug Interactions).

WARNINGS

Dependence and Withdrawal Reactions, Including Seizures

Certain adverse clinical events, some life-threatening, are a direct consequence of physical dependence to XANAX. These include a spectrum of withdrawal symptoms; the most important is seizure. Even after relatively shortterm use at the doses recommended for the treatment of transient anxiety and anxiety disorder (ie, 0.75 to 4.0 mg per day), there is some risk of dependence. Spontaneous reporting system data suggest that the risk of dependence and its severity appear to be greater in patients treated with doses greater than 4 mg/day and for long periods (more than 12 weeks). However, in a controlled postmarketing discontinuation study of panic disorder patients, the duration of treatment (3 months compared to 6 months) had no effect on the ability of patients to taper to zero dose. In contrast, patients treated with doses of XANAX greater than 4 mg/day had more difficulty tapering to zero dose than those treated with less than 4 mg/day.

Side Effects

Xanax For Sale Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Reasons for stopping Alprazolam treatment immediately If you get any of these symptoms, see your doctor straight away as treatment will need to be discontinued. Your doctor will then advise how treatment will be stopped.

• Very occasionally treatment with Alprazolam can cause serious behavioural or psychiatric effects – for example agitation, restlessness, aggressiveness, irritability, violent anger, false beliefs, nightmares and hallucinations or other inappropriate behaviour.

• Sudden wheeziness, difficulty in swallowing or breathing, swelling of eyelids, face or lips, rash or itching (especially affecting the whole body).

Dependence and withdrawal symptoms

• It is possible to become dependent on medicines like Alprazolam while you are taking them which increases the likelihood of getting withdrawal symptoms when you stop treatment.

• Withdrawal symptoms are more common if you:

– stop treatment suddenly

– have been taking high doses

– have been taking this medicine for a long time

– have a history of alcohol or drug abuse.

This can cause effects such as headaches, muscle pain, extreme anxiety, tension, restlessness, confusion, mood changes, difficulty sleeping and irritability. In severe cases of withdrawal you can also get the following symptoms: nausea (feeling sick), vomiting, sweating, stomach cramps, muscle cramps, a feeling of unreality or detachment, being unusually sensitive to sound, light or physical contact, numbness and tingling of the feet and hands, hallucinations (seeing or hearing things which are not there while you are awake), tremor or epileptic fits.

Other side effects that may occur are: Very common: may affect more than 1 in 10 people

• Depression

• Sleepiness and drowsiness

• Jerky, uncoordinated movements

• Inability to remember bits of information

• Slurred speech

• Dizziness, light-headedness

• Headaches

• Constipation

• Dry mouth

• Tiredness

• Irritability.

Common: may affect up to 1 in 10 people

• Loss of appetite

• Confusion and disorientation

• Increased or decreased sex drive (men and women) and sexual dysfunction

• Nervousness or feeling anxious or agitated

• Insomnia (inability to sleep or disturbed sleep)

• Problems with balance, and unsteadiness (similar to feeling drunk) especially during the day

• Loss of alertness or concentration

• Inability to stay awake, feeling sluggish

• Shakiness or trembling

• Double or blurred vision

• Feeling sick

• Skin reactions

• Change in your weight.

Uncommon: may affect up to 1 in 100 people

• Feeling elated or over-excited, which causes unusual behaviour

• Hallucination (seeing or hearing things that do not exist)

• Feeling agitated or angry

• Incontinence

• Cramping pain in the lower back and thighs, which may indicate menstrual disorder

• Muscle spasms or weakness

• Vomiting

• Drug dependence

• Withdrawal syndrome.

Xanax Dosage

Xanax For Sale Dosage Information

The Xanax dosage your doctor prescribes will depend on several factors. These include:

  • the condition you’re taking Xanax to treat and its severity
  • your age
  • the form of Xanax you take*
  • your liver function
  • other medical conditions you may have
  • other medications you may take
  • side effects you may have with Xanax

Xanax doses are not determined by weight.

Typically, your doctor will start you on a low dosage. Then they’ll adjust it over time to reach the amount that’s right for you. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect.

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Xanax form and strengths (0.25 mg, 0.5 mg, 1 mg, and 2 mg)

Xanax comes as an oral tablet that’s available in four strengths: 0.25 milligrams (mg), 0.5 mg, 1 mg, and 2 mg.

Xanax tablet colors: White, peach, or blue

The color and shape of Xanax tablets vary by strength:

  • 0.25 mg: white, oval
  • 0.5 mg: peach, oval
  • 1 mg: blue, oval
  • 2 mg: white, rectangle with rounded corners

Dosage for generalized anxiety disorder

To treat generalized anxiety disorder (GAD) in adults, the typical starting dosage of Xanax is 0.25 mg to 0.5 mg, three times per day.

It’s possible that your doctor will adjust your dose every 3 to 4 days until you’re taking the dose that’s right for you. This depends on how you respond to the starting dosage.

The maximum recommended dosage for GAD is 4 mg per day, split into three doses.

Dosage for panic disorder

To treat panic disorder in adults, the recommended starting dosage of Xanax is 0.5 mg three times per day.

It’s possible that your doctor will adjust your dose every 3 to 4 days until you’re taking the dose that’s right for you. This depends on how you respond to the starting dosage. Your dose should be increased by no more than 1 mg per day.

The average dosage for panic disorder is 5 mg to 6 mg per day, split into three doses. However, some people may need up to 10 mg per day, split into three doses.

Dose Titration

Treatment may be initiated with a dose of 0.5 mg three times daily. Depending on the response, the dose may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. Slower titration to the dose levels greater than 4 mg/day may be advisable to allow full expression of the pharmacodynamic effect of XANAX. To lessen the possibility of interdose symptoms, the times of administration should be distributed as evenly as possible throughout the waking hours, that is, on a three or four times per day schedule.

Generally, therapy should be initiated at a low dose to minimize the risk of adverse responses in patients especially sensitive to the drug. Dose should be advanced until an acceptable therapeutic response (ie, a substantial reduction in or total elimination of panic attacks) is achieved, intolerance occurs, or the maximum recommended dose is attained.

Dose Maintenance

For patients receiving doses greater than 4 mg/day, periodic reassessment and consideration of dosage reduction is advised. In a controlled postmarketing dose-response study, patients treated with doses of XANAX greater than 4 mg/day for 3 months were able to taper to 50% of their total maintenance dose without apparent loss of clinical benefit. Because of the danger of withdrawal, abrupt discontinuation of treatment should be avoided.

The necessary duration of treatment for panic disorder patients responding to XANAX is unknown. After a period of extended freedom from attacks, a carefully supervised tapered discontinuation may be attempted, but there is evidence that this may often be difficult to accomplish without recurrence of symptoms and/or the manifestation of withdrawal phenomena.

Dose Reduction

In all patients, dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. Although there are no systematically collected data to support a specific discontinuation schedule, it is suggested that the daily dosage be decreased by no more than 0.5 mg every three days. Some patients may require an even slower dosage reduction.

In any case, reduction of dose must be undertaken under close supervision and must be gradual. If significant withdrawal symptoms develop, the previous dosing schedule should be reinstituted and, only after stabilization, should a less rapid schedule of discontinuation be attempted. In a controlled postmarketing discontinuation study of panic disorder patients which compared this recommended taper schedule with a slower taper schedule, no difference was observed between the groups in the proportion of patients who tapered to zero dose; however, the slower schedule was associated with a reduction in symptoms associated with a withdrawal syndrome. It is suggested that the dose be reduced by no more than 0.5 mg every 3 days, with the understanding that some patients may benefit from an even more gradual discontinuation. Some patients may prove resistant to all discontinuation regimens.

Xanax precautions

Xanax For Sale Precautions

FDA warnings

This drug has boxed warnings Trusted Source. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). It alerts doctors and patients about drug effects that may be dangerous.

Risk of misuse and addiction. Xanax has a risk of misuse and addiction. With misuse, a drug is taken for a purpose or in a way that a doctor has not prescribed. Misuse can lead to addiction, which is when you’re unable to stop taking a drug, even though it may be causing harm. To learn more, see the “Xanax misuse and addiction” section above.

Risk of dependence and withdrawal. Xanax has a risk of dependence and withdrawal. With dependence, your body becomes reliant on a drug to function as usual. Dependence can lead to withdrawal symptoms if you suddenly stop taking the drug. For more information, see the “Xanax dependence and withdrawal” section above.

Risk of severe harm or death if taken with opioids. Taking Xanax with an opioid may cause severe side effects. These can include excessive sleepiness, breathing problems, coma, and in rare cases, death. Due to these risks, doctors will typically not prescribe Xanax with an opioid unless no other treatment options are suitable.

Opioids are powerful drugs that are also known as opiates or narcotics. They include strong prescription pain relievers, such as hydrocodone (Hysingla ER) and certain illegal drugs. For more examples, see the “Xanax interactions” section above.

If your doctor does prescribe Xanax with an opioid, they’ll prescribe the lowest possible dosage of both medications for the shortest possible time.* Be sure to tell people you live with, your caregiver, and people close to you that you’re taking these medications together. You or another person should call 911 right away if:

  • you become very sleepy or unresponsive
  • your breathing becomes slow and shallow
  • your breathing stops altogether

Also, you should not drive or perform other potentially dangerous activities, such as operating machines, until you know how the drug combination affects you.

For more information about this boxed warning, talk with your doctor.

Other precautions

Before taking Xanax, talk with your doctor about your health history. Xanax may not be right for you if you have certain medical conditions or other factors affecting your health. These include:

  • Allergic reaction. If you’ve ever had an allergic reaction to Xanax or any of its ingredients, your doctor will likely not prescribe Xanax. Also, if you’ve ever had an allergic reaction to other benzodiazepine drugs, such as diazepam (Valium) or lorazepam (Ativan), your doctor will likely not prescribe Xanax. (Xanax is a benzodiazepine drug.) Taking Xanax could cause another allergic reaction. You can ask your doctor what other medications may be better options for you.
  • Older age. If you’re age 65 years or older, you may have an increased risk of side effects with Xanax. These include sleepiness, dizziness, and problems with coordination that may raise your risk of falls. Due to these risks, your doctor will likely prescribe a dosage of Xanax that’s lower than usual.
  • Liver problems. Your liver breaks down Xanax in your body. If you have a liver problem, such as alcoholic liver disease, Xanax may build up in your body. This can increase your risk of side effects. Due to this risk, your doctor will likely prescribe a dosage of Xanax that’s lower than usual.
  • Kidney problems. Your kidneys help remove Xanax from your body. If you have a kidney problem, such as kidney failure, you may have an increased risk of side effects with Xanax. Your doctor may prescribe a Xanax dosage that’s lower than usual.
  • Breathing problems. Xanax can cause breathing problems, such as slowed breathing. If you have a lung or breathing problem, such as chronic obstructive pulmonary disease (COPD) or sleep apnea, Xanax could make your condition worse. You can talk with your doctor about whether Xanax is right for you.
  • Depression or bipolar disorder. Xanax may worsen depression or cause episodes of mania in people with depression. If you have a history of depression or bipolar disorder, talk with your doctor about whether Xanax is right for you.
  • Pregnancy. Whether Xanax is safe to take during pregnancy may depend on how far along the pregnancy is. For more information, see the “Xanax and pregnancy” section above.
  • Breastfeeding. Breastfeeding is not recommended while taking Xanax.

6 reviews for Xanax XR 0.5mg

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